Nuclear Receptors
NRs are a class of proteins that act as gene-expression regulating factors. They are classified into eight subfamilies:
- NR1: Thyroid hormone like (TR, RAR, ROR, PPAR, VDR)
- NR2: HNF4-like (HNF4, RXR, TLL, COUP, USP)
- NR3: Estrogen like (ER, ERR, GR, MR, PR, AR)
- NR4: Nerve Growth factor IB-like (NGFIB, NURR)
- NR5: Fushi tarazu-F1 like (SF1, FTF, FTZ-F1)
- NR6: Germ cell nuclear factor like (GCNF1)
- NR0A: Knirps like (KNI, KNRL, EGON, ODR7) (no LBD)
- NR0B: DAX like (DAX - SHP) (no DBD)
